Bank Rec Statement End Balance and Unresolved aren't matching

SUGGESTED

I've had an amount left unresolved for November bank rec which I haven't been able to figure out so I have reversed my last reconciliation (Oct) and started again.

Oct opening and end balance in Sage 50 matches my bank statement before I've started my Oct reconciliation. I ticked/reconciled all Oct transactions and unresolved is now at zero. So I post the Oct rec.

Then the opening and end balance in Sage 50 matches my bank statement for Nov 1 to Nov 30. Before I even start my reconciliation with no transactions ticked/reconciled, my unresolved is not a negative match to my statement end balance. There is a difference of approx $5,068.39. 

I've never had this before and I don't want to proceed with the reconciliation knowing that it will be out this much at the end (at least).

Any suggestions on what I can do to resolve?