The help files in Sage CRM are authored in Adobe FrameMaker and then converted to HTML using Quadralay's WebWorks software.

Adobe FrameMaker: http://www.adobe.com/products/framemaker/
Quadralay WebWorks: http://www.quadralay.com/

At some point in the near future the Documentation team will be moving to use Madcap Software's Flare tool to generate the Web based Help output.

Madcap Flare: http://www.madcapsoftware.com/products/flare/