New Quote Summary/Header

We need to add a a lot more fields to the quote screen header. I don't want to make summary/header field extremely large. What I'm wanting to do is add another block/section that is visible once a drop down is selected as x - custom. I'm thinking that this can be done with runblock. https://community.sagecrm.com/partner_community/b/hints_tips_and_tricks/archive/2012/12/17/creating-a-codeless-extra-entry-tab-for-a-system-entity-using-runblock.aspx

But I'm not sure how to implement this on the quotes as I'm concerned about how it interacts with the line items (QuoteItems).

Thanks,

Jake