Sage 300 Sage CRM 7.2 integration

Hello

I have installed Sage crm version 7.2 and 300 version 7.5. I have installed the integration and in CRM, while Synchronizing with 300 data base I am getting the following error.

Anyone can help me with this error??

Error Opening the Sage 300 ERP Company SMXSYS.
Name='Error'

Message='Permission denied'

Number=-2146828218

Description='Permission denied'

Operation='Opening ACCPAC.Session object.'

Thank You Kari-Ann