Sage 100 does not have a web interface for clients.  They need to run the Windows workstation software, and for remote users that is usually done through a terminal server.

Sage 100 is a Windows application requiring a Windows network connection between the workstation and server. WindX based clients still require the network connection

I once tried running 100 on Linux using Crossover. I was successful getting a one user install going. Due to the network requirements and Crossover's lack of Windows network support that was the end of the road for that effort. FWIW 100 did seem to run faster on Linux.