Unable to connect with the System Manager Database. Pervasive ODBC Client Interface Client LNA... no available transport protocol for the Pervasive Network Service Layer

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We are running Windows 10 with a Server 2012 Datacenter server.  Everything has been running along just fine and now the clients are getting the above error.  I have read something about a Microsoft update and have tried uninstalling and reinstalling at the client but now getting errors to just reinstall and nothing is working... ANY HELP???  Thanks