Yes, we have had clients successfully setup Microsoft Graph, do you have any details on what version and update is installed? 

I am using 2022 PU3

We have seen security and anti-virus programs preventing Sage 300 from interacting with Microsoft.  Can you check to see if there is any attempt in Azure Active Directory to sign-in.

There is monitoring for User Sign-ins (Non-interactive), which will show for each interaction.  The resource should be listed as Microsoft Graph, which will have a request ID for each interaction. 

As well, Fiddler by telerik can help to diagnose issues, when sending test email there will be a tunnel to graph.microsoft.com, and a response.

We have seen security and anti-virus programs preventing Sage 300 from interacting with Microsoft.  Can you check to see if there is any attempt in Azure Active Directory to sign-in.

There is monitoring for User Sign-ins (Non-interactive), which will show for each interaction.  The resource should be listed as Microsoft Graph, which will have a request ID for each interaction. 

As well, Fiddler by telerik can help to diagnose issues, when sending test email there will be a tunnel to graph.microsoft.com, and a response.