I must be going senile in my old age. I ran into this issue 4 years ago and found a workaround. The only difference is this time we weren't getting an error message pop up, the application just freezes.

Solution:

(This solution is for a 64 bit machine.  On a 32 bit machine simply omit the references to Wow6432Node.)

Open the registry, navigate to HKLM\Software\Wow6432Node\Accpac International, Inc.
Export this key to a .reg file. (this export will include all subkeys and values).
Edit that .reg file, replacing evey reference to

[HKEY_LOCAL_MACHINE\SOFTWARE\WOW6432Node\

with

[HKEY_CURRENT_USER\Software\Classes\VirtualStore\MACHINE\SOFTWARE\WOW6432Node\

.Now log in as the affected user, and import the edited .reg file. (You can just double click on it to invoke the registry import).

[1] Note that on a 64 bit computer, the actual location of the above registry key is \HKLM\Software\WOW6432Node\Accpac International, Inc., due to Registry Redirection and Reflection. – However, as far as the 32 bit programs are concerned, it is seen as being at \HKLM\Software\Accpac International, Inc..  This is not the cause of the problem.

Source: Modulo eImagepac and Sage 300 Ops Inquiry Registry Virtualisation (UAC Virtualisation) Error - Business Software Tasmania (bussofttas.com.au)

I must be going senile in my old age. I ran into this issue 4 years ago and found a workaround. The only difference is this time we weren't getting an error message pop up, the application just freezes.

Solution:

(This solution is for a 64 bit machine.  On a 32 bit machine simply omit the references to Wow6432Node.)

Open the registry, navigate to HKLM\Software\Wow6432Node\Accpac International, Inc.
Export this key to a .reg file. (this export will include all subkeys and values).
Edit that .reg file, replacing evey reference to

[HKEY_LOCAL_MACHINE\SOFTWARE\WOW6432Node\

with

[HKEY_CURRENT_USER\Software\Classes\VirtualStore\MACHINE\SOFTWARE\WOW6432Node\

.Now log in as the affected user, and import the edited .reg file. (You can just double click on it to invoke the registry import).

[1] Note that on a 64 bit computer, the actual location of the above registry key is \HKLM\Software\WOW6432Node\Accpac International, Inc., due to Registry Redirection and Reflection. – However, as far as the 32 bit programs are concerned, it is seen as being at \HKLM\Software\Accpac International, Inc..  This is not the cause of the problem.

Source: Modulo eImagepac and Sage 300 Ops Inquiry Registry Virtualisation (UAC Virtualisation) Error - Business Software Tasmania (bussofttas.com.au)