We have had our system setup since back before SAGE moved to MSSQL (2010 or earlier) to automatically populate the PO number with the next available PO Number automatically and have never had any issues with it.  As of about a week ago it started failing (populating the field with a random string that doesn't even match our PO Number format) with one of our smaller companies.  As of today all companies (4 out of 4) are failing.  Anyone else seeing this?