Question about removing local administrative rights for Sage 50 US users

SUGGESTED

Hi, we use Sage 50 US edition ver 2021.  We have five Sage users on Windows 10 connecting to a Windows Server 2012r2 server running Sage 50.  We are required to remove local admin privileges for employees for security reasons, and make them standard users on the domain.  There is also one Sage Intelligence Reporting user.  How will this effect Sage?  Thanks.